Cardiotonic means widely use for treatment of heart failure. A long time cardiac glycosides were almost only means, at changing for this purpose. In an acute heart failure sometimes applied adrenaline, and further began at to change more modern adrenomimetichesky drugs (see KIzadrii, Dopamine, Dobutaminum). Recently there were new cardiotonics negliko a zidny and not adrenergic pririda (see Amrinon), however the main cardiotonics applied to treatment of chronic heart failure continue to remain cardiac glycosides.
It is necessary to consider that recently tactics of medicinal therapy of heart failure became more perfect. Along with the drugs stimulating sokratitelny activity of a myocardium the means reducing load of a myocardium and facilitating cardiac performance, reducing a metabolic cost of a cardiac muscle and improving thus its function not by stimulation, and its more economical activity are widely used. Such means of complex therapy are first of all Uperifericheskiye the vazodilatator (see) reducing pre- and an afterload by a myocardium by reduction of peripheric vascular resistance and expansion of a peripheral vascular bed and also K diuretic means reducing load of a myocardium, having hypovolemic effect, i.e. reducing the volume of the circulating blood plasma.
In a certain measure cardiotonic properties oblyadat the means having the general positive impact on metabolic processes of an organism including metabolism of a myocardium (see. Anabolic hormones, Inosine, etc.).