Справочник лекарств
Каталог лекарств
The alkaloids and other vegetable matters having cytostatic impact (6)
The alkylating substances (24)
Amino acids (10)
Analgesic means (56)
Vasoprotectives (10)
Anorexigenic means (3)
Antagonists of calcium ions (8)
Antiarrhytmic drugs (15)
Antigiperlipoproteinemichesky (anti-atherosclerotic) means (11)
Antimetabolites (24)
Antiseptics (87)
Vitamins and related drugs (66)
Hepatoprotective means (8)
Antihypertensives (10)
Histamine and antihistaminic drugs (22)
Hormone. Ven., their antagonists applied mainly at treatment oncological a disease (14)
Hormones, their analogs and anti-hormonal drugs (93)
Diuretic means (25)
Dopamine and dofaminergichesky drugs (2)
Bile-expelling means (16)
Immunosuppressive drugs (immunosuppressors) (6)
Cardiotonic means (18)
Expectorants (25)
Plasma substituting and disintoxication solutions (23)
Drugs for parenteral nutrition (12)
Drugs for prevention and treatment of radiation sickness (5)
The drugs substituting synovial and plaintive liquids (0)
The drugs used for correction of an acid-base state and ionic balance in organiz (48)
The drugs stimulating processes of immunity (13)
Prostaglandin and their synthetic derivatives (2)
Antineoplastic antibiotics (10)
Anticonvulsants (17)
Different diagnostic means (5)
Different drugs the stimulating metabolic processes (56)
Emetic and antiemetic drugs (7)
X-ray contrast means (13)
Sahara (2)
Serotonin, serotonergic and antiserotoninovy drugs (6)
Synthetic antineoplastic drugs of different groups (5)
Depletive (30)
Sleeping medicines (11)
Special means for treatment of alcoholism (4)
Specific antidotes; sorbents; complexons (15)
Means for treatment of parkinsonism (14)
Anesthetics (14)
The means influencing fibrillation (34)
The means operating on peripheral cholinergic processes (57)
The means operating mainly on peripheral adrenergic processes. (38)
The means increasing arterial blood pressure (2)
The means lowering sensitivity of nerve terminations (55)
The means relaxing muscles of a uterus (tokolitika) (4)
The means stimulating uterus muscles (17)
The means stimulating receptors of mucous membranes, skin and hypodermic fabrics (31)
The means which are slowing down formation of uric concrements and facilitating their removal with urine (20)
The means improving blood supply of bodies and fabrics (48)
Fermental drugs and inhibitors of enzymes (35)
The enzymes applied to treatment of oncological diseases (1)
The photosensitizing and photoprotective drugs (6)
Cholelitholytic means (2)
New drugs on the website (1)
Psychotropic drugs (112)
Khimioterapevticheskiyey means (221)
Last comments
04.07.2016 - HOPE
03.07.2016 - Ella
03.07.2016 - Ira
29.06.2016 -
23.06.2016 -
20.06.2016 - Natalya
18.06.2016 -
18.06.2016 - the novel
16.06.2016 - Elena
15.06.2016 - the Hairpin

Hormone. Ven., their antagonists applied mainly at treatment oncological a disease

Androgenic drugs
Gestagenny drugs, (progestins)
Inhibitors of biosynthesis of hormones of an adrenal gland
Estrogenic drugs
In oncological practice a number of hormonal drugs, first of all androgens is used (see Drugs of male sex hormones Testosterone, etc.), corticosteroids are oestrogenic (see Drugs of female sex hormones Estrone, etc.) (see Drugs of bark of adrenal glands the Cortisone, etc.). Recently the drugs which are slowing down effect of estrogen (anti-estrogen) and androgens (anti-androgens) became widespread also. Some drugs (hloditan, aminoglutethimide) specifically suppress secretion by adrenal glands of glucocorticosteroids (cortisol).
These drugs are used mainly in hormonedependent tumors. Estrogen is appointed when suppression of action in an organism of androgens or strengthening of activity of estrogen is shown (in a prostate cancer). Androgens apply when increase in activity of androgens or reduction of activity of estrogen is shown (in a breast cancer, etc.). In a breast cancer and a uterus applies also progestins (pregnenoldione caproate, a medroksiprogesterona acetate, megestrol acetate). When reduction of secretion of glucocorticosteroids (is shown in Itsenko's disease of Cushing, etc.), apply blockers of function of adrenal glands.
Glucocorticosteroids, in connection with their limfolitichesky action and ability to oppress a mitosis of lymphocytes, apply mainly in acute leukoses (mainly at children) and malignant lymphoma.
On the action mechanism hormonal drugs differ from cytotoxic antineoplastic drugs. Their main role - restoration of the broken humoral regulation of function of cells. At the same time, their specific influence on tumor cells is not excluded: they to some extent slow down cell fission and promote their differentiation. Estrogen stimulates education with a liver of the globulin connecting androgens and reducing concentration freely, the circulating testosterone; they oppress also 5 Aa - reductase, i.e. reduce transformation of testosterone into the dihydrotestosterone playing an important role in development of tumoral process.
Estrogen oppresses release from a front share of a hypophysis of luteinizing hormone that leads to decrease in products of androgens testicles.
An important role in the mechanism of antineoplastic effect of hormones is played by their linking with receptors, specific to them, which existence is revealed not only in normal target tissues, but also in some tumors.
Antineoplastic effect give different estrogenic, androgenic and other hormonal drugs in the corresponding hormonedependent tumors. However, for practical application in oncology a number of drugs with<выгодными> the most therapeutic and toxicological indicators is selected.

© medicine-cure.com - the reference book of drugs, 2016
Attention! Information on the website is intended only for workers of health care!