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Phepranonum

instruction for use



PHEPRANONUM (Phepranonum). 1-Fenil-2-dietilamino-1-propanona hydrochloride.

Synonyms: Abulemin, Amfepramone, Amfepramonum, Amphepramon, Anorex 'Orto', Danulen, Diethylpropion, Dobesin, Keramm, Natorexic, Parabolin, Regenon, Tenuate, Tepanil, etc.

Crystal powder of bitter taste, white or white with slightly creamy shade. Let's easily dissolve in water and alcohol.

Phepranonum can be considered as Phenaminum analog, however features of the chemical building cause some differences in pharmacological properties of these connections.

Drug has anorexigenic activity. Compared with Phenaminum, Phepranonum has weak exciting impact on central nervous system and affects peripheral adrenergic structures a little, i.e. possesses a little more selective anorexigenic effect.

The indication to use of Phepranonum is mainly exogenous (alimentary) obesity; it can be also applied in an adiposagenital syndrome (in combination with hormonal therapy), at a hypothyroidism (in combination with Thyreoidinum) and other forms of obesity. Treatment is carried out in combination with a low-calorie diet, if necessary - with fasting days.

Appoint inside in the form of tablets 0, 025 g (25 mg) 2 - 3 times a day for half an hour or hour to food (breakfasts and a lunch). At good tolerance and insufficient effect it is possible to increase a dose to 4 tablets a day. Course of treatment 1, 5 - 2, 5 months. If necessary conduct repeated courses with breaks of 3 months.

Phepranonum is usually well transferred. However at persons with hypersensitivity and at overdose, emergence of irritability, insomnia, dryness in a mouth, nausea, a constipation or a diarrhea and other by-effects is possible. When prescribing drug and in a hyperthyroidism the care is necessary for persons with diseases of a cardiovascular system.

Treatment has to be carried out under thorough observation of the doctor.

Drug is contraindicated at pregnancy, far come hypertension forms, the significant disturbances of cerebral and coronary circulation, a myocardial infarction, a thyrotoxicosis, glaucoma, tumors of a hypophysis and adrenal glands, diabetes, the increased nervous irritability, epilepsy, psychoses, sharp sleep disorders. It is not necessary to appoint drug the patient accepting monoamine oxidase inhibitors (see Nialamidum).

Not recomenduyeteya to take the drug in the second half of day (in order to avoid a sleep disorder).

Packaging: tablets on 0, 025 (25 mg) in packing on 50 pieces.

Storage: A.V list the dry, protected from light place. It is released only on the prescription of the doctor.


It is applied at treatment:
Obesity
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