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instruction for use

NOSPANUM (No-Spa). 1-(3, 4-Diethoxybenzal)-6, 7-diethoxy-1, 2, 3, 4 tetrahydroisoquinolines hydrochloride.

Synonyms: Drotaverinum, Drotaverine hydrochloride, Deprolen, Dihydroethaverine, Nospan, Nospasin, Tetraspasmin.

Crystal substance of flavourless light yellow color. Let's dissolve in water and alcohol. On the chemical building and pharmacological action it is very close to a papaverine, has stronger and more long spasmolytic activity.

NOSPANUM (No-Spa) apply at spasms of a stomach and intestines, spastic constipations, attacks bilious and an urolithiasis, a peptic ulcer of a stomach and a duodenum (it is better in combination with cholinolytics), sometimes at spasms of peripheral vessels (an endarteritis, etc.).

Accept inside 0, 04 - 0, 08 g (1 - 2 tablets) 2 - 3 times a day. If necessary enter the same dose (2 - 4 ml of 2% of solution) intramusculary. At attacks of hepatic and renal colic and stenocardia enter 2 - 4 ml of 2% of solution intravenously (slowly!). At disturbances of peripheric circulation (obliterating endarteritis) is vnutriarterialno entered sometimes (slowly!).

To children appoint in smaller doses according to age (1/4 1/2 tablets 1 - 2 times a day).

The drug NOSPANUM (No-Spa) is usually well transferred. At parenteral administration the feeling of heat, dizziness, heartbeat, perspiration are possible. Cases of an allergic dermatosis are described.

Packagings: tablets on 0, 04 g in packing on 100 pieces; 2% solution in ampoules on 2 ml (0, 04 g) in packing on 5 or 50 ampoules. Storage: list B.

Nicospanum. The combined drug which part Nospanum and niacin are.

The combination of these substances provides the increased vasodilating effect (see Niacin). By the principle of action drug is close to Nicoverinum (see).

Apply at angiospasms of a brain and disturbances of peripheric circulation - (the alternating lameness, a thromboangitis, etc.).

Appoint inside 1 - 3 tablet a day (after a meal) or on 1 2 ml (1/2 - 1 ampoule) under skin or intramusculary 1 - 2 time a day. If necessary enter slowly into a vein 1 ml of solution. In disorders of peripheric circulation (obliterating thromboangitis) enter (slowly) into a femoral artery 1 - 2 ml of solution.

At Nicospanum use perhaps temporary face reddening, then all body, feeling of heat. These phenomena are especially expressed at administration of drug on an empty stomach and connected with pharmacological action of the components entering drug (see Niacin, Nospanum and also the tablets 'Nicoverinum').

Packagings: tablets on 0, 078 g (78 mg) of Nospanum and 0, 022 g (22 mg) of niacin; in ampoules on 0, 0642 g (64, 2 mg) of Nospanum and 0, 0176 g (17, 6 mg) of niacin (in 2 ml).

On action of a tablet 'Nikoverin' (see) are very close to Nicospanum.

Storage: list B.

Bispanum (Bispanum). The combined drug produced in the form of the tablets containing on Oh, 06 g (60 mg) of Nospanum and 0, 005 g (5 mg) of cholinolytic drug of an izopropamid (2, 2-diphenyl-4-diisopropyl-aminobutyramide).

Apply in enterospasms, a spastic colitis, acute and chronic hyperacid gastritis, a peptic ulcer of a stomach and duodenum, a cholecystopathy, spasms of the ureters and other diseases which are followed by spasms of unstriated muscles of internals.

Appoint inside for adults in sharp cases 1 - 2 tablet 2 - 3 times a day; in chronic cases - on 1 tablet 2 - 3 times a day for 3 - 4 weeks.

Contraindications: prostatauxe and glaucoma (especially closed-angle form).

Storage: list B.

It is manufactured in Hungary.

It is applied at treatment:
Algodismenorey, hypertension, Asthma bronchial, Dysmenorrhea, Constipations, Pancreatitis, Arterial hypertension, Bronchial asthma, Hypertension

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